Before LSD escaped the lab and was evangelized by hippies, the U.S. government was secretly testing the effects of the drug on hundreds of unsuspecting American civilians and military personnel. In a must-read feature on newly unclassified material on the Central Intelligence Agency’s covert operation, the MK-ULTRA program, which ran from 1953 to 1964, SF Weekly fully exposes the bizarre world of the CIA’s unethical drug tests.  The utterly-unbelievable-but-true story involved using hookers to lure in unwitting johns for undisclosed testing, narcotics agents who slipped drugs into drinks, and a U.S. marshal who held up a San Francisco bar not knowing he was high on acid.

It sounds like something out of a paranoid dream. And indeed, before the documentation and other facts of the program were made public, those who talked of it were frequently dismissed as being psychotic. But the U.S. government’s history of secret human experimentation ought to be kept in mind, particularly when we consider the power we grant to it and the way we regulate drugs.

The LSD experiments were purportedly carried out because the U.S. believed that communist Russia, North Korea and China were using the drug to brainwash captured Americans. Consequently, the CIA didn’t want to fall behind in developing and responding to this potentially useful technology.

So, incredibly, it decided to slip acid secretly to Americans — at the beach, in city bars, at restaurants. For a decade, the CIA conducted completely uncontrolled tests in which they drugged people unknowingly, then followed and watched them without intervening. In some cases, the agency used the drug to perform interrogations, but these procedures were conducted so inconsistently that they proved equally useless in providing useful data.

MORE: Magic Mushrooms Expand the Mind By Dampening Brain Activity

The lack of ethical controls was even more appalling. Here’s how SF Weekly’s Troy Hooper describes what happened to one of the last living survivors of the MK-ULTRA operation:

It’s been over 50 years, but Wayne Ritchie says he can still remember how it felt to be dosed with acid.