Junk food-addicted rats chose to starve themselves rather than eat healthy food

(NaturalNews) A diet including unlimited amounts of junk food can cause rats to become so addicted to the unhealthy diet that they will starve themselves rather than go back to eating healthy food, researchers have discovered.

In a series of studies conducted over the course of three years and published in the journal Nature Neuroscience, Scripps Florida scientists Paul Johnson and Paul Kenny have shown that rats' response to unlimited junk food closely parallels well-known patterns of
drug addiction -- even down to the changes in brain chemistry.

"What we have are these core features of
addiction, and these animals are hitting each one of these features," Kenny said.

In their first study, the researchers fed rats on either a balanced diet or on the same diet plus unlimited access to junk foods purchased at a local supermarket, including processed meats and cakes. Within a short time period, the rats on the
junk food diet began to eat compulsively and quickly became overweight.

"They're taking in twice the amount of calories as the control rats," Kenny said.

The researchers hypothesized that the rats were
eating compulsively because, like drug addicts, they had become desensitized to smaller amounts and needed more and more for the same rush of pleasure.

Many recreational drugs work by directly stimulating the brain's pleasure centers, particularly the dopamine receptor known as D2. Overstimulation of this receptor causes the body to start producing less dopamine, leading the addict to compensate by taking more of the drug.

Since dopamine can also be released by pleasurable activities such as
food or sex, Kenny and Johnson speculated that food addiction could develop in the same way. To test whether the rats had, in fact, become habituated to dopamine, the researchers took the rats from the first experiment and hooked their brains up to a device that would directly stimulate their D2 receptors when they ran on a wheel.

Rats eating a junk food diet ran on the wheel significantly longer than rats fed a normal diet, suggesting that their receptors had indeed become desensitized. This "profound" desensitization occurred after just five days on a junk food diet.

"They're not experiencing rewards the way they should," Kenny said. "When you experience that, one way of feeling better is to go back to the junk food."

"They lose control. This is the hallmark of addiction."

In another test of their addiction hypothesis, the researchers used a virus to block the D2 receptors in healthy rats. All those rats soon became compulsive eaters.

"This is the most complete evidence to date that suggests
obesity and drug addiction have common neurobiological underpinnings," Johnson said.

Having established that the junk food rats had become addicted, Johnson and Kenny wanted to know how far this addiction would push them. So they took both junk-food addicted rats and rats that had not previously been exposed to such food, and exposed them to electrical shocks whenever they ate junk. Rats that had just been introduced to junk food quickly stopped eating it, while the addicted rats ignored the discomfort and kept eating.

Perhaps the most shocking finding came when the researchers took away the addicted rats' access to junk food and started feeding them only healthy rat chow again -- the same diets the rats had eaten as pups. When junk food was no longer available, the rats simply refused to eat for two weeks.

"They actually voluntarily starved themselves," Kenny said.

"It's almost as if you break these things, it's very, very hard to go back to the way things were before. Their dietary preferences are dramatically shifted."

The
research strongly suggests that many modern humans also suffer from junk food addictions. Kenny notes, however, that unlike the rats, all humans with access to junk food do not become obese. He attributes this difference to the influence of health knowledge and social pressure in moderating people's natural eating habits.

"The rats don't suffer from the same social pressures that we do," he said.

The idea of junk food addiction is not a new one, and the dopamine-junk food connection was actually put forward by former FDA Commissioner David Kessler in his best-selling book, The End of Overeating.

"Certainly, we see this addictive pattern in humans," nutritionist Sandy Livingston said. "They know they shouldn't overeat, but they do it anyway."

Livingston expressed hope that better knowledge about the biochemical side of food addiction might result in lessened guilt and judgment surrounding obesity.

"A lot of people blame themselves -- 'Why don't I have any willpower?'" she said.

"Food can be highly addictive," said author and nutritional supplement producer Jordan Rubin. "When people describe
overeating and weight loss as a battle, this is why."

He called for more research into which individual components of junk food, such as MSG, might be behind its addictive effects.

Obesity researcher Ralph DiLeone of Yale University noted that more research is needed into the long-term effects of such addiction, even if an animal later switches its diet and loses
weight.

"They might be a normal weight, but how they respond to food in the future may be permanently altered," he said.

Suggesting yet another area for future research, Kenny has expressed hope that better biochemical understanding of food addiction might someday enable the development of a drug or vaccine as a treatment for compulsive eating.

Johnson and Kenny's research was funded by grants from the National Institutes of Health, Bank of America and The Margaret Q. Landenberger Research Foundation.

Sources for this story include:

http://www.palmbeachpost.com/health... http://www.sciencenews.org/view/gen....

Views: 56

Comment

You need to be a member of 12160 Social Network to add comments!

Join 12160 Social Network

"Destroying the New World Order"

TOP CONTENT THIS WEEK

THANK YOU FOR SUPPORTING THE SITE!

mobile page

12160.info/m

12160 Administrators

 

Latest Activity

Doc Vega posted a blog post

Buying the Last haunted House on the Left (A partial autobiography)

Not to the reader there ever events here that are true and some that are fictional.Chapter IIt was…See More
2 hours ago
Doc Vega posted a blog post

In Memory of Those Who Served

 Bullets flew and ricochetedI was on that hill todayMy Company commander got blown awayI was on…See More
yesterday
Doc Vega posted blog posts
Tuesday
Doc Vega commented on Doc Vega's blog post Plausible Explanation Behind Recent Cryptid Sightings in the Wild!
"cheeki kea I was wrong Emperor Penguins are big and powerful but still alive but this,  A size…"
Tuesday
Doc Vega commented on Doc Vega's blog post Plausible Explanation Behind Recent Cryptid Sightings in the Wild!
"Cheeki kea here's another that they say there have been modern sightings of!  The name of…"
Tuesday
Doc Vega commented on Doc Vega's blog post Plausible Explanation Behind Recent Cryptid Sightings in the Wild!
"cheeki kea, did you ever hear of the giant Imperial Penguins? They were about 6 feet tall and could…"
Tuesday
Doc Vega commented on Doc Vega's blog post Plausible Explanation Behind Recent Cryptid Sightings in the Wild!
"cheeki kea I do not think these giant two legged birds would need to have a bad attitude as long as…"
Tuesday
Olivia Brooks updated their profile
Tuesday
John Miller was featured
Tuesday
tjdavis's 2 blog posts were featured
Tuesday
Zfort Group's blog post was featured
Tuesday
Doc Vega's 6 blog posts were featured
Tuesday
Burbia commented on tjdavis's video
Thumbnail

“What’s His Motive?” - Inside The Mind of George Soros

"Trump calls for George Soros and son to face federal…"
Tuesday
Burbia commented on tjdavis's photo
Tuesday
Profile IconSeeta Sathe and Olivia Brooks joined 12160 Social Network
Tuesday
tjdavis posted a video

Mossad, Terrifying CIA Technology, Blackwater & The Most Secret CIA Unit | John Kiriakou

John Kiriakou served 15 years in the CIA as a Case Officer (Spy) and as CIA's Head of Counterterrorism Operations in Pakistan where he lead the raid that cap...
Monday
tjdavis posted a photo
Monday
tjdavis posted a video

A Critique of the Tavistock Institute - The Mother Of All Conspiracy Theories

An examination of the Tavistock Institute, a theory which seeks to explain how Western societies have been brainwashed by a cabal of social scientists and th...
Sunday
tjdavis posted a video

“What’s His Motive?” - Inside The Mind of George Soros

In this short clip, Patrick Bet-David, Sebastian Gorka Adam Sosnick, and Tom Ellsworth George Soros and what motivates him to do the things he does. FaceTime...
Aug 27
Doc Vega posted blog posts
Aug 27

© 2025   Created by truth.   Powered by

Badges  |  Report an Issue  |  Terms of Service

content and site copyright 12160.info 2007-2019 - all rights reserved. unless otherwise noted