• The artificial sweetener industry has defended the safety of sucralose (Splenda), stating that it rapidly passes through your body without being broken down and therefore has no biological effects
• Research reveals your body does indeed metabolize sucralose and that it accumulates in your fat cells. Two new metabolites have also been identified. As these findings were not part of the original regulatory decision process for sucralose, researchers are calling for a review of its safety and regulatory status
• Sucralose causes definite changes in the liver of treated rats, suggesting toxic effects. According to the researchers, sucralose should be used with caution to avoid liver damage
• Previous research found sucralose reduces gut bacteria by 50 percent, increases the intestinal pH level and causes biochemical distortions. This was again confirmed in 2018, when all currently approved artificial sweeteners were found to cause DNA damage in, and interfere with, the normal and healthy activity of gut bacteria
• Consuming artificial sweeteners such as sucralose, aspartame, saccharin, neotame, advantame and/or acesulfame potassium-k can impair your appetite regulation and cause weight gain

https://articles.mercola.com/sites/articles/archive/2019/02/06/sucr...