The specific objective of the In vivo Nanoplatforms for Diagnostics (IVN:Dx) thrust of the In vivo Nanoplatforms (IVN) program is to develop biocompatible nanosensors that provide continuous, noninvasive, and highly accurate measurement of a variety of conditions and substances within the living tissue of animals, plants, and insects using non-toxic materials with limited immunogenicity. These sensors will permit qualitative and quantitative assessment over large concentration ranges of both small (e.g., glucose, lactate, and urea) and large molecules (e.g., proteins, oligonucleotides, infectious agents, and chemical/biological threat agents) in the organism and environment through optical, electronic, thermal or magnetic mechanisms.

See the attached DARPA-BAA-12-33 document.